Down I-95 through five states before the Carolinas
A truck loading around Boston works a loop through the suburbs and the South Shore, sometimes adds Providence, then runs I-95 through Connecticut, crosses into New York on I-287 or the Cross Bronx, and takes the New Jersey Turnpike south. From there it is the same I-95 corridor everyone runs: Delaware, Baltimore, the Beltway, Richmond, the Carolinas, Georgia and Jacksonville. Drivers cover 450 to 550 miles a day, so the first Florida deliveries are on the fourth day.
Where the truck can and cannot go
Door-to-door is the standard. Suburban streets inside and outside 128 are fine; drivers come to Newton, Lexington, Wellesley, Needham, Milton, Hingham and the like. Boston proper, Brookline's narrower streets, Cambridge and Somerville are not. A 75-foot truck meets customers at a lot on Route 1 in Saugus or Dedham, along I-93 or at a mall off 128.
Have this ready
One key, a quarter tank, the Fast Lane transponder out of the windshield, and belongings under about 100 pounds and uninsured. Photograph every panel and the odometer before the truck arrives and keep the bill of lading from pickup to compare at delivery.